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Sweet syndrome (SS), or acute febrile neutrophilic dermatosis, [1] [2] is a skin disease characterized by the sudden onset of fever, an elevated white blood cell count, and tender, red, well-demarcated papules and plaques that show dense infiltrates by neutrophil granulocytes on histologic examination.
There are many diseases known to cause ocular or visual changes. Diabetes , for example, is the leading cause of new cases of blindness in those aged 20–74, with ocular manifestations such as diabetic retinopathy and macular edema affecting up to 80% of those who have had the disease for 15 years or more.
The most common areas of involvement are the skin (also known as leukemia cutis) and the gums. Skin involvement typically appears as violaceous, raised, nontender plaques or nodules, which on biopsy are found to be infiltrated with myeloblasts [ 6 ] Note that leukemia cutis differs from Sweet's syndrome , in which the skin is infiltrated by ...
Sweet's syndrome-like dermatosis is a cutaneous condition associated with bowel disorders. [1] See also. Sweet's syndrome; List of cutaneous conditions; References
Cogan syndrome: Inner ear and eye None specific Probable [99] Graves' ophthalmopathy: Eye muscles and connective tissue TSH receptor antibodies Confirmed [100] Intermediate uveitis: Uvea Various Probable [101] Ligneous conjunctivitis: Conjunctiva: Plasminogen deficiency Possible Rare [102] Mooren's ulcer: Cornea: None specific Probable Rare [103]
The etiology of multiple evanescent white dot syndrome is currently unknown but two potential origins have been postulated. Gass, et. al. suggests a virus invades retinal photoreceptors through cell-to-cell transmission via either the ora serrata or optic disc margin. [3]
Involvement of the eye is rarely the initial symptom but develops in 60% of persons with RP. [ 3 ] [ 6 ] [ 4 ] [ 8 ] [ 9 ] The most common forms of ocular involvement are usually mild and often consist of unilateral or bilateral episcleritis and/or scleritis , that is often anterior and could be lingering or relapsing.
Typically, brain and eye involvement occur on the same side as the port-wine stain. Over time, port-wine stains can develop soft tissue or bone hypertrophy, proliferative nodules, and progressive ectasia which can lead to significant disfigurement. [45] The two most common ocular manifestations include glaucoma and choroidal hemagioma.