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Particular medications can result in MRONJ, a serious but uncommon side effect in certain individuals. Such medications are frequently used to treat diseases that cause bone resorption such as osteoporosis, or to treat cancer. The main groups of drugs involved are anti-resorptive drugs, and anti-angiogenic drugs.
Local anaesthetic is used routinely for dental procedures in oral surgery, restorative, periodontal, and prosthetic dentistry. Infiltration injections are a safe and effective method for dealing with daily dental procedures and dental pain. [4] Nevertheless, some complications can arise from infiltrations.
Similarly to bisphosphonates, denosumab appears to be implicated in increasing the risk of osteonecrosis of the jaw (ONJ) following extraction of teeth or oral surgical procedures but, unlike bisphosphonate, the risk declines to zero approximately 6 months after injection. [23] Invasive dental procedures should be avoided during this time.
Intraosseous anaesthetic injection involves the deposition of anaesthetic solution directly into the cancellous alveolar bone adjacent to the apex of the root of the tooth to be anaesthetised through a small hole. Additionally, more complex dental procedures like surgery or endodontic therapy (like root canals) might make use of it.
Dental antibiotic prophylaxis is the administration of antibiotics to a dental patient for prevention of harmful consequences of bacteremia, that may be caused by invasion of the oral flora into an injured gingival or peri-apical vessel during dental treatment.
There are many circumstances during dental treatment where antibiotics are prescribed by dentists to prevent further infection (e.g. post-operative infection). The most common antibiotic prescribed by dental practitioners is penicillin in the form of amoxicillin, however many patients are hypersensitive to this particular antibiotic.
Adverse effects depend on the local anesthetic method and site of administration discussed in depth in the local anesthetic sub-article, but overall, adverse effects can be: localized prolonged anesthesia or paresthesia due to infection, hematoma, excessive fluid pressure in a confined cavity, and severing of nerves & support tissue during ...
Articaine is a dental amide-type local anesthetic. It is the most widely used local anesthetic in a number of European countries [ 2 ] and is available in many countries. It is the only local anaesthetic to contain a thiophene ring , meaning it can be described as 'thiophenic'; this conveys lipid solubility.