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Auditory processing disorder (APD), rarely known as King-Kopetzky syndrome, is a neurodevelopmental disorder affecting the way the brain processes sounds. [2] Individuals with APD usually have normal structure and function of the ear, but cannot process the information they hear in the same way as others do, which leads to difficulties in recognizing and interpreting sounds, especially the ...
The syndrome can be difficult to diagnose and may be misdiagnosed as autism, pervasive developmental disorder, hearing impairment, learning disability, auditory processing disorder, attention deficit hyperactivity disorder (ADHD), intellectual disability, childhood schizophrenia, or emotional/behavioral problems. An EEG (electroencephalogram ...
Central auditory processing disorder This is not an actual hearing loss but gives rise to significant difficulties in hearing. One kind of auditory processing disorder is King-Kopetzky syndrome , which is characterized by an inability to process out background noise in noisy environments despite normal performance on traditional hearing tests.
It is often due to diffuse axonal injury and demyelination. There may be peripheral and central symptoms, such as reduced auditory understanding in a complex listening environment, central auditory processing disorder and auditory hallucination. [23] Hyperacusis, that is the hypersensitivity to environmental noise can also develop. [24]
Spatial hearing loss can be diagnosed using the Listening in Spatialized Noise – Sentences test (LiSN-S), [25] which was designed to assess the ability of children with central auditory processing disorder (CAPD) to understand speech in background noise.
In August 2020, the U.S. Food and Drug Administration (FDA) became aware of nitrosamine impurities in certain samples of rifampin. [61] The FDA and manufacturers are investigating the origin of these impurities in rifampin, and the agency is developing testing methods for regulators and industry to detect the 1-methyl-4-nitrosopiperazine (MNP ...
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Rifampin rapidly kills fast-dividing bacilli strains as well as "persisters" cells, which remain biologically inactive for long periods of time that allow them to evade antibiotic activity. [7] In addition, rifabutin and rifapentine have both been used against tuberculosis acquired in HIV-positive patients.