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Electron-beam processing involves irradiation (treatment) of products using a high-energy electron-beam accelerator. Electron-beam accelerators utilize an on-off technology, with a common design being similar to that of a cathode ray television. Electron-beam processing is used in industry primarily for three product modifications:
Electron beam therapy is used in the treatment of superficial tumors like cancer of skin regions, or total skin (e.g. mycosis fungoides), diseases of the limbs (e.g. melanoma and lymphoma), nodal irradiation, and it may also be used to boost the radiation dose to the surgical bed after mastectomy or lumpectomy.
Intraoperative electron radiation therapy is the application of electron radiation directly to the residual tumor or tumor bed during cancer surgery. [1] [2] Electron beams are useful for intraoperative radiation treatment because, depending on the electron energy, the dose falls off rapidly behind the target site, therefore sparing underlying healthy tissue.
IORT is typically a component in the multidisciplinary treatment of locally advanced and recurrent cancer, in combination with external beam radiation, surgery, and chemotherapy. As a growing trend in recent years, IORT can also be used in earlier stage cancers such as prostate and breast cancer.
Targeted intra-operative radiotherapy, also known as targeted IORT, is a technique of giving radiotherapy to the tissues surrounding a cancer after its surgical removal, a form of intraoperative radiation therapy.
External beam radiation therapy (EBRT) is a form of radiotherapy that utilizes a high-energy collimated beam of ionizing radiation, from a source outside the body, to target and kill cancer cells. The radiotherapy beam is composed of particles, which are focussed in a particular direction of travel using collimators [ 1 ] .
Research in this area has focused on the three most common sources of radiation used for these applications, including gamma, electron beam, and x-ray radiation. [17] The mechanisms of radiation damage are different for polymers and metals, since dislocations and grain boundaries do not have real significance in a polymer.
Electron-beam machining is a process in which high-velocity electrons are concentrated into a narrow beam with a very high planar power density. The beam cross-section is then focused and directed toward the work piece, creating heat and vaporizing the material. Electron-beam machining can be used to accurately cut or bore a wide variety of metals.