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The median lethal dose (LD 50) is estimated to be 50–500 mg/kg in humans. [34] Symptoms of overdose may include dry mouth, dilated pupils, insomnia, night terrors, euphoria, hallucinations, seizures, rhabdomyolysis, and death. [35] Fatalities have been reported from doxylamine overdose.
The symptoms of this dementia depend on where in the brain the strokes occurred and whether the blood vessels affected were large or small. [13] Repeated injury can cause progressive dementia over time, while a single injury located in an area critical for cognition such as the hippocampus, or thalamus, can lead to sudden cognitive decline. [72]
It is the cause of 60–70% of cases of dementia. [2] [15] The most common early symptom is difficulty in remembering recent events. [1] As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and behavioral issues. [2]
After adjusting for sociodemographic and lifestyle factors, family history of dementia, baseline cognitive function and medications that affect cognition, the researchers analyzed whether there ...
Repeated use of a certain class of drugs for heartburn was linked with a higher risk for dementia among patients in Germany, researchers say. Gastric reflux drugs may be tied to dementia risk Skip ...
Amnesic shellfish poisoning (ASP) is an illness caused by consumption of shellfish that contain the marine biotoxin called domoic acid. [1] In mammals, including humans, domoic acid acts as a neurotoxin, causing permanent short-term memory loss, brain damage, and death in severe cases.
A link between these types of drugs and cognitive impairment isn't a totally new discovery, but for the first time, researchers used brain imaging techniques to determine the physical changes ...
At this time they begin exhibiting symptoms of radiation poisoning of sufficient severity to render them totally ineffective. Death follows for about half of males at approximately six weeks after exposure. Nausea and vomiting generally occur within 24–48 hours after exposure to mild (1–2 Gy) doses of radiation.