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Lubiprostone, sold under the brand name Amitiza among others, is a medication used in the management of chronic idiopathic constipation, predominantly irritable bowel syndrome -associated constipation in women and opioid-induced constipation. The drug is owned by Mallinckrodt and is marketed by Takeda Pharmaceutical Company.
Constipation is more concerning when there is weight loss or anemia, blood is present in the stool, there is a history of inflammatory bowel disease or colon cancer in a person's family, or it is of new onset in someone who is older. [12] Treatment of constipation depends on the underlying cause and the duration that it has been present. [4]
Sodium picosulfate is a prodrug. [5] It has no significant direct physiological effect on the intestine; however, it is metabolised by gut bacteria into the active compound 4,4'-dihydroxydiphenyl- (2-pyridyl)methane (DPM, BHPM). [5][6] This compound is a stimulant laxative and increases peristalsis in the gut. [5][7]
Sodium thiosulfate is a classical antidote to cyanide poisoning, [10] For this purpose it is used after the medication sodium nitrite and typically only recommended for severe cases. [4] [6] It is given by injection into a vein. [4] In this use, sodium nitrite creates methemoglobinemia which removes cyanide from mitochondria. [6]
In terms of bonding, isocyanates are closely related to carbon dioxide (CO 2) and carbodiimides (C (NR) 2). The C−N=C=O unit that defines isocyanates is planar, and the N=C=O linkage is nearly linear. In phenyl isocyanate, the C=N and C=O distances are respectively 1.195 and 1.173 Å. The C−N=C angle is 134.9° and the N=C=O angle is 173.1°.
Melanoma mostly occurs on the sun-exposed parts of the skin (i.e. those that show when you wear a bathing suit) including your head, neck, back, shoulders, and arms, ...
Glycerin suppositories used as laxatives. Laxatives, purgatives, or aperientsare substances that loosen stools[1]and increase bowel movements. They are used to treat and prevent constipation. Laxatives vary as to how they work and the side effects they may have.
Acne blemishes are most common on the face, chest, back, shoulders and neck, but they can appear almost anywhere. With acne, you might have pimples, blackheads, papules, pustules, cysts or nodules ...
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