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  2. Acquired generalized lipodystrophy - Wikipedia

    en.wikipedia.org/wiki/Acquired_generalized...

    Acquired generalized lipodystrophy (AGL), also known as Lawrence syndrome[1] and Lawrence–Seip syndrome, [1] is a rare skin condition that appears during childhood or adolescence, characterized by fat loss affecting large areas of the body, particularly the face, arms, and legs. [2]: 496 There are four types of lipodystrophy based on its ...

  3. Lipodystrophy - Wikipedia

    en.wikipedia.org/wiki/Lipodystrophy

    Endocrinology. Lipodystrophy syndromes are a group of genetic or acquired disorders in which the body is unable to produce and maintain healthy fat tissue. [1][2] The medical condition is characterized by abnormal or degenerative conditions of the body's adipose tissue. A more specific term, lipoatrophy (from Greek lipo 'fat' and dystrophy ...

  4. Congenital generalized lipodystrophy - Wikipedia

    en.wikipedia.org/wiki/Congenital_generalized...

    Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder which manifests with insulin resistance, absence of subcutaneous fat and muscular hypertrophy. [5] Homozygous or compound heterozygous mutations in four genes are associated with the four subtypes of CGL. [3] The condition appears in early childhood with ...

  5. Marfan syndrome - Wikipedia

    en.wikipedia.org/wiki/Marfan_syndrome

    Marfan syndrome (MFS) is a multi-systemic genetic disorder that affects the connective tissue. [6][7][1] Those with the condition tend to be tall and thin, with long arms, legs, fingers, and toes. [1] They also typically have exceptionally flexible joints and abnormally curved spines. [1]

  6. Lipedema - Wikipedia

    en.wikipedia.org/wiki/Lipedema

    Lipedema is a medical condition that is almost exclusively found in women [3] and results in enlargement of both legs due to deposits of fat under the skin. [2] Women of any weight may develop lipedema [2][3] and the fat associated with lipedema is resistant to traditional weight-loss methods. [4] There is no cure and typically it gets worse ...

  7. Familial partial lipodystrophy - Wikipedia

    en.wikipedia.org/wiki/Familial_partial_lipodystrophy

    Familial partial lipodystrophy, also known as Köbberling–Dunnigan syndrome, [2] is a rare genetic metabolic condition characterized by the loss of subcutaneous fat. [3]: 495. FPL also refers to a rare metabolic condition in which there is a loss of subcutaneous fat in the arms, legs and lower torso. The upper section of the body, face, neck ...

  8. MDP syndrome - Wikipedia

    en.wikipedia.org/wiki/MDP_syndrome

    MDP syndrome. MDP syndrome, also known as mandibular dysplasia with deafness and progeroid features, is an extremely rare metabolic disorder that prevents fatty tissue from being stored underneath the skin. It is only known to affect a very small number of people worldwide (fewer than 12 cases have been diagnosed as of December 2014).

  9. Major depressive episode - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_episode

    A major depressive episode (MDE) is a period characterized by symptoms of major depressive disorder. Those affected primarily exhibit a depressive mood for at least two weeks or more, and a loss of interest or pleasure in everyday activities. Other symptoms can include feelings of emptiness, hopelessness, anxiety, worthlessness, guilt ...