Search results
Results from the WOW.Com Content Network
The causes of neonatal hepatitis are many. Viruses that have been identified include cytomegalovirus, rubella virus, hepatitis A and B viruses, herpes simplex viruses, coxsackievirus, echovirus, and paramyxovirus. [2] Metabolic and immune disorders can also cause neonatal hepatitis. [2] Giant cell transformation throughout the parenchyma is ...
Neonatal cholestasis can present in newborn infants within the first few months of life. [1] The incidence of neonatal cholestasis is approximately 1 in 2,500 term births. [ 5 ] While neonatal cholestasis can present from a number of pathologic causes, 35-40% of neonatal cholestasis cases are caused by biliary atresia . [ 3 ]
Syndromic biliary atresia (e.g. Biliary Atresia Splenic Malformation (BASM)) has been associated with certain genes (e.g. Polycystic Kidney Disease 1 Like 1 - PKD1L1 [6]), and some infants with isolated biliary atresia may arise as a result of an autoimmune inflammatory response, possibly due to a viral infection of the liver soon after birth. [7]
Autoimmune hepatitis vs. hepatitis C. Having nothing to do with hepatitis A, B or C, autoimmune hepatitis (AIH) is caused by an autoimmune reaction that tells the body to attack its liver.
Neonatal jaundice is a yellowish discoloration of the white part of the eyes and skin in a newborn baby due to high bilirubin levels. [1] Other symptoms may include excess sleepiness or poor feeding. [1] Complications may include seizures, cerebral palsy, or kernicterus. [1] In most of cases there is no specific underlying physiologic disorder. [2]
The scan is also important to differentiate between neonatal hepatitis and biliary atresia, because an early surgical intervention in form of Kasai portoenterostomy or hepatoportoenterostomy can save the life of the baby as the chance of a successful operation after 3 months seriously decreases. [9]
Hepatitis A, B, and D are preventable via vaccination. Hepatitis A can be prevented by immunization against HAV, while Hepatitis B and D can both be prevented by immunization against HBV. [20] The Hepatitis B vaccination is among the first two injections a newborn receives. [48] The other is vitamin K to prevent vitamin K deficiency bleeding. [49]
Her research interests lie in the fields of the genetics of neonatal liver disease, management and treatment of pediatric liver disease, particularly focusing on auto-immune liver disease, viral hepatitis, biliary atresia, cholestatic liver disease and the long term outcome following liver transplantation. [3]