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In dermatopathology, the Tzanck test, also Tzanck smear, is scraping of an ulcer base to look for Tzanck cells. It is sometimes also called the chickenpox skin test and the herpes skin test. It is a simple, low-cost, and rapid office based test. [1] Tzanck cells (acantholytic cells) are found in: Herpes simplex [2] Varicella and herpes zoster
Dermatology Acantholysis is the loss of intercellular connections , such as desmosomes , resulting in loss of cohesion between keratinocytes , [ 1 ] seen in diseases such as pemphigus vulgaris . [ 2 ]
Dermatology Grover's disease ( GD ) is a polymorphic, pruritic , papulovesicular dermatosis characterized histologically by acantholysis [ 2 ] : 529 with or without dyskeratosis. [ 3 ] Once confirmed, most cases of Grover's disease last six to twelve months, which is why it was originally called "transient".
Many skin conditions require a skin biopsy for confirmation of the diagnosis. With several of these conditions there are features within the cells contained in the skin biopsy specimen that have elements in their cytoplasm or nucleus that have a characteristic appearance unique to the condition. These elements are termed inclusion bodies.
Suture granuloma, with multinucleated giant cells surrounding (grey) suture material. Foreign bodies indicate a foreign body granuloma. Specific forms of multinucleated giant cells include the Touton giant cell, which contains a ring of nuclei surrounding a central homogeneous cytoplasm, with foamy cytoplasm surrounding the nuclei.
Acantholytic dyskeratotic epidermal nevus is a cutaneous condition identical to the generalized form of Darier's disease. [ 1 ] : 849 "Acantholytic dyskeratotic epidermal nevus" is probably the same disorder.
The formula includes lipo-hdydroxy acid — LHAs — which gently renews the skin cell-by-cell to lead to surface exfoliation that unveils brighter skin with fewer wrinkles and age spots.
Dermatology: Lethal acantholytic epidermolysis bullosa is a fatal genetic skin disorder caused by mutations in DSP [1] [2] [3]