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Renal dysplasia is a type of familial kidney disease characterized by abnormal cellular differentiation of kidney tissue. Dogs and cats with kidney disease caused by these diseases have the typical symptoms of kidney failure, including weight loss, loss of appetite, depression, and increased water consumption and urination. [1]
It can result in chronic kidney failure, hypoalbuminemia, which can cause ascites and peripheral edema, and nephrotic syndrome, which can cause hypertension or hypercoagulability. [156] Familial renal disease is an uncommon cause of kidney failure in young dogs. Most causes are breed-related (familial) and some are inherited.
The disease is specific to the Samoyed, in that the Samoyed is the only breed of dog to show the more rapid progression to kidney failure and death, as well as affecting males to a much more severe degree than females. The Samoyed, however, is not the only breed of dog to suffer from life-threatening renal diseases.
The reason some dogs develop kidney failure following ingestion of grapes and raisins is not known. [3] Types of grapes involved include both seedless and seeded, store-bought and homegrown, and grape pressings from wineries. [4] A mycotoxin is suspected to be involved, but none has been found in grapes or raisins ingested by affected dogs. [5]
Early symptoms include intoxication, vomiting and abdominal pain. [1] Later symptoms may include a decreased level of consciousness, headache, and seizures. [1] Long term outcomes may include kidney failure and brain damage. [1] Toxicity and death may occur after drinking even in a small amount [1] as ethylene glycol is more toxic than other diols.
Shunting the issue - Liver shunts in dogs. This article will discuss what exactly a liver shunt is, how to recognize the signs of a liver shunt, what treatment options are available, and how to ...
Skin conditions in dogs are very common, so it's important to recognize the symptoms and understand the factors that cause them. Dr. Rebecca MacMillan, a vet with over 15 years of experience, says ...
[2] [3] The high number of affected dogs at the Greenetrack Racing Park, Alabama, led to the initial pseudonyms of Greenetrack Disease and Alabama Rot. [4] The initial symptoms are skin lesions on the legs, chest and abdomen followed by renal involvement. [2] [3] In November 2012 the first cases were suspected in the UK. [5]
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