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Most individuals with G6PD deficiency are asymptomatic.When it induces hemolysis, it is usually is short-lived. [5]Most people who develop symptoms are male, due to the X-linked pattern of inheritance, but female carriers can be affected due to unfavorable lyonization or skewed X-inactivation, where random inactivation of an X-chromosome in certain cells creates a population of G6PD-deficient ...
G6PD converts G6P into 6-phosphoglucono-δ-lactone and is the rate-limiting enzyme of the pentose phosphate pathway. Thus, regulation of G6PD has downstream consequences for the activity of the rest of the pentose phosphate pathway. Glucose-6-phosphate dehydrogenase is stimulated by its substrate G6P.
A map of the Philippines showing the island groups of Luzon, the Visayas, and Mindanao. As an archipelago, the Philippines comprises about 7,641 islands [1] [2] clustered into three major island groups: Luzon, the Visayas, and Mindanao. Only about 2,000 islands are inhabited, [3] and more than 5,000 are yet to be officially named. [2]
The wettest recorded typhoon to hit the Philippines dropped 2,210 millimeters (87 in) in Baguio from July 14 to 18, 1911. [58] The Philippines is highly exposed to climate change and is among the world's ten countries that are most vulnerable to climate change risks. [59] Building construction is undertaken with natural disasters in mind.
The Philippines, [g] officially the Republic of the Philippines, [h] is an archipelagic country in Southeast Asia. In the western Pacific Ocean , it consists of 7,641 islands , with a total area of roughly 300,000 square kilometers, which are broadly categorized in three main geographical divisions from north to south: Luzon , Visayas , and ...
There are 100 volcanoes in the Philippines listed by the Smithsonian Institution's Global Volcanism Program (GVP) at present, [6] of which 20 are categorized as "historical" and 59 as "Holocene". [6] The GVP lists volcanoes with historical, Holocene eruptions, or possibly older if strong signs of volcanism are still evident through thermal ...
The more than 140 cities in the Philippines as of 2022 have taken their names from a variety of languages both indigenous (Austronesian) and foreign (mostly Spanish).The majority of Philippine cities derive their names from the major regional languages where they are spoken including Tagalog (), Cebuano, Ilocano, Hiligaynon, Bicolano, Kapampangan and Pangasinense.
This is a complete list of cities and municipalities in the Philippines. The Philippines is administratively divided into 82 provinces ( Filipino : lalawigan ). These, together with the National Capital Region , are further subdivided into cities (Filipino: lungsod ) and municipalities (Filipino: bayan ).