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However, the definition of a read-through gene in the CCDS data set is that the individual partner genes must be distinct, and the read-through transcripts must share ≥ 1 exon (or ≥ 2 splice sites except in the case of a shared terminal exon) with each of the distinct shorter loci. [2]
The genetic code is a key part of the history of life, according to one version of which self-replicating RNA molecules preceded life as we know it. This is the RNA world hypothesis . Under this hypothesis, any model for the emergence of the genetic code is intimately related to a model of the transfer from ribozymes (RNA enzymes) to proteins ...
Gene nomenclature is the scientific naming of genes, the units of heredity in living organisms. It is also closely associated with protein nomenclature, ...
Gene has been implemented at NCBI to characterize and organize the information about genes. It serves as a major node in the nexus of the genomic map, expression, sequence, protein function, structure, and homology data. A unique GeneID is assigned to each gene record that can be followed through revision cycles.
This was the approach of the investigation and identification of Halomonas zincidurans strain B6(T), a bacterium with thirty-one genes encoding resistance to heavy metals, especially zinc [71] and Stenotrophomonas sp. DDT-1, a strain capable of using DDT as its sole carbon and energy source, [72] to mention a few examples.
Ab Initio gene prediction is an intrinsic method based on gene content and signal detection. Because of the inherent expense and difficulty in obtaining extrinsic evidence for many genes, it is also necessary to resort to ab initio gene finding, in which the genomic DNA sequence alone is systematically searched for certain tell-tale signs of protein-coding genes.
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GENCODE is a scientific project in genome research and part of the ENCODE (ENCyclopedia Of DNA Elements) scale-up project.. The GENCODE consortium was initially formed as part of the pilot phase of the ENCODE project to identify and map all protein-coding genes within the ENCODE regions (approx. 1% of Human genome). [2]