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The usual appearance of portal hypertensive gastropathy on endoscopy is a mosaic-like or reticular pattern in the mucosa. Red spots may or may not be present. The pattern is usually seen throughout the stomach. [2] A similar pattern can be seen with a related condition called gastric antral vascular ectasia (GAVE), or watermelon stomach.
Endoscopy often reveals classic diffuse raised plaques that characteristically can be removed from the mucosa by the endoscope. Brushing or biopsy of the plaques shows yeast and pseudohyphae by histology that are characteristic of Candida species.
The endoscopic appearance in eosinophilic gastroenteritis is nonspecific; it includes erythematous, friable, nodular, and occasional ulcerative changes. [21] Sometimes diffuse inflammation results in complete loss of villi, involvement of multiple layers, submucosal oedema and fibrosis. [22] [23]
Diagram of the alkaline mucous layer in the stomach with mucosal defense mechanisms. The gastric mucosa is the mucous membrane layer of the stomach, which contains the gastric pits, to which the gastric glands empty. In humans, it is about one mm thick, and its surface is smooth, soft, and velvety.
The diagnosis of lymphocytic esophagitis is made by biopsy of the mucosal lining of the esophagus. This is typically achieved at the time of esophagogastroduodenoscopy, a medical procedure wherein an endoscope is inserted through the mouth, into the esophagus, in order to visualize and biopsy the mucosa. [citation needed]
Esophagitis can be diagnosed by upper endoscopy, biopsy, upper GI series (or barium swallow), and laboratory tests. [4] An upper endoscopy is a procedure to look at the esophagus by using an endoscope. While looking at the esophagus, the doctor is able to take a small biopsy. The biopsy can be used to confirm inflammation of the esophagus.
Endoscopy with biopsies of the esophagus has a 100% sensitivity and 96% specificity for diagnosing eosinophilic esophagitis. [8] Biopsy specimens from both the proximal/mid and distal esophagus should be obtained regardless of the gross appearance of the mucosa. Specimens should also be obtained from areas revealing endoscopic abnormalities.
The appendix has a mucosa resembling the colon but is heavily infiltrated with lymphocytes. Transition between the different types of epithelium occurs at the junction between the oesophagus and stomach; between the stomach and duodenum, between the ileum and caecum, and at the pectinate line of the anus. [1]