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The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation of the immune system. [1] The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals. [2] Mutations in HLA genes may be linked to ...
The discovery of the MHC and role of histocompatibility in transplantation was a combined effort of many scientists in the 20th century. A genetic basis for transplantation rejection was proposed in a 1914 Nature paper by C.C. Little and Ernest Tyyzer, which showed that tumors transplanted between genetically identical mice grew normally, but tumors transplanted between non-identical mice were ...
n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a n/a Wikidata View/Edit Human major histocompatibility complex, class II, DP alpha 1 Identifiers Symbol HLA-DPA1 Alt. symbols HLA-DP1A NCBI gene 3113 HGNC 4938 OMIM 142880 RefSeq NM_033554 UniProt P20036 Other data Locus Chr. 6 p21.3 Search for Structures Swiss-model ...
Fluidigm to Develop and Supply a Custom High-throughput Prep System for HLA Typing Custom system will ultimately enable DKMS Life Science Lab to type several thousand samples per week SOUTH SAN ...
On 1 Oct. 2002, the Army formed IMA as a field operating agency of the Assistant Chief of Staff for Installation Management (ACSIM) as part of an ongoing effort to realign installations. [15] Many of the issues with the 15 major commands holding responsibility for base support was that the structure created many inequities throughout the Army ...
The HLA Informatics Group (HIG), led by Professor Steven Marsh at the Anthony Nolan Research Institute, is dedicated to advancing the field of immunogenetics.Their primary focus is on the study of genetic diversity within human populations, particularly in relation to the human leukocyte antigen (HLA) system.
In 1968 the WHO Nomenclature Committee for Factors of the HLA System first met. [3] They established a system that divided the HLAs into HLA-A and HLA-B, A and B corresponding to a group of reactive serotypes. For example, "HL-A2" became HLA-A2, "HL-A7" became HLA-B7 and "HL-A8" became HLA-B8.
HLA-NET is a network targeted to the study of Human leukocyte antigen (HLA) from a populational point of view. The network was initiated by COST Action BM0803 [ 1 ] in January 2009. Currently HLA-NET activities are being coordinated by a subcommittee of the scientific committee of the European Federation for Immunogenetics .