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Curative therapy is indicated in early stages, which include very early stage (single nodule <2 cm), curable by surgical resection (survival 50-70% five years after surgical resection) and early stage (single nodule of 2–5 cm, or up to 3 nodules <3 cm) which can be treated by radiofrequency ablation (RFA) and liver transplantation.
Currently, if the hepatic adenoma is >5 cm, increasing in size, symptomatic lesions, has molecular markers associated with HCC transformation, rising level of liver tumor markers such as alpha fetoprotein, the patient is a male, or has a glycogen storage disorder, the adenoma is recommended to be surgically removed. [7]
The Liver Imaging Reporting and Data System (aka LI-RADS) is a quality assurance tool created and trademarked by the American College of Radiology in 2011 to standardize the reporting and data collection of CT and MR imaging patients at risk for hepatocellular carcinoma (HCC), or primary cancer of the liver cells. [1]
Barcelona Clinic Liver Cancer classification [50] [51] [52] Stage Description Child-Pugh class ECOG performance status 0 (very early stage) Single nodule, < 3 cm: A: 0 A (early stage) 1–3 nodule, all < 3 cm: A or B B (intermediate stage) Multi-nodular tumor C (advanced stage) Portal invasion and extra-hepatic spread: 1 or 2 D (terminal stage ...
Nodular regenerative hyperplasia (NRH) is a rare liver disease, characterised by the growth of nodules within the liver, resulting in liver hyperplasia.While in many cases it is asymptomatic and thus goes undetected – or is only discovered incidentally while investigating some other medical condition – in some people it results in non-cirrhotic portal hypertension (NCPH).
Liver tumor types by relative incidence in adults in the United States, with focal nodular hyperplasia at right. [ 3 ] Focal nodular hyperplasia's most recognizable gross feature is a central stellate scar seen in 60–70% of cases.
Given that several liver tumors appear similarly on these imaging modalities, a multi-phase contrast-enhanced imaging study such as CT or MRI may be used to provide more information. [ 3 ] [ 4 ] The significance of making a specific diagnosis is that, unlike other benign liver tumors such as hemangioma and focal nodular hyperplasia, hepatic ...
In the axial plane, the caudate lobe should normally have a cross-section of less than 0.55 of the rest of the liver. [2] Other ultrasound studies have suggested hepatomegaly as being defined as a longitudinal axis > 15.5 cm at the hepatic midline, or > 16.0 cm at the midclavicular line. [17] [18]