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[citation needed] DMARDs can be further subdivided into traditional small molecular mass drugs synthesised chemically and newer "biological" agents produced through genetic engineering. Some DMARDs (e.g. the purine synthesis inhibitors ) are mild chemotherapeutics , but use a side effect of chemotherapy— immunosuppression —as their main ...
Conventional DMARDs are known to be the first-line treatment for rheumatoid arthritis. [9] Treatment can be a monotherapy or in combination with other anti-arthritic medications. Common DMARDs include oral methotrexate, leflunomide, or sulfasalazine. Conventional DMARDs have a slow onset of action and can take 2–3 months to exhibit effect. [9]
Steroids may be injected into affected joints during the initial period of RA, prior to the use of DMARDs or oral steroids. [151] Non-NSAID drugs to relieve pain, like paracetamol may be used to help relieve the pain symptoms; they do not change the underlying disease. [5] The use of paracetamol may be associated with the risk of developing ...
Drug resistance is the reduction in effectiveness of a medication such as an antimicrobial or an antineoplastic in treating a disease or condition. [1] The term is used in the context of resistance that pathogens or cancers have "acquired", that is, resistance has evolved.
Steroid ring system. This is a list of corticosteroids (glucocorticoids and mineralocorticoids) or derivatives of cortisol (hydrocortisone). Most esters of these ...
This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
Insulin resistance, or low insulin sensitivity, happens when cells throughout the body don’t respond properly to the hormone insulin, especially cells in muscles, fat and the liver.
Drugs with similar structures and biological activity are also banned because new designer drugs of this sort are always being developed in order to beat the drug tests. Caffeine, a stimulant known to improve performance, is currently not on the banned list. It was listed until 2004, with a maximum allowed level of 12 micrograms per millilitre ...