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Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]
Dengue fever is a mosquito-borne disease caused by dengue virus, prevalent in tropical and subtropical areas. It is frequently asymptomatic; if symptoms appear, they typically begin 3 to 14 days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin itching and skin rash. Recovery ...
Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
The disease, which includes symptoms such as a high fever and body aches, is endemic — or ever present — in many parts of the world, including Puerto Rico and other U.S. territories.
Most dengue fever patients recover in a week, but in severe cases the disease can be life-threatening and require hospitalization since it can result in shock, internal bleeding and even death.
The second dengue virus infection can be fatal, especially if the infected person develops severe dengue. The World Health Organization (WHO) has noted that having a previous infection with the dengue virus significantly increases the risk of developing severe dengue. This risk increases considerably even further if the second infection is ...
NITD is a small molecule drug discovery research institute. [1]Research is currently focused on three main diseases: [2] dengue fever; malaria; tuberculosis.; NITD's research model relies on global partnership with other research institutes. [1]
Treatment of acute dengue is supportive, using either oral or intravenous rehydration for mild or moderate disease, and intravenous fluids and blood transfusion for more severe cases. The incidence of dengue fever has increased dramatically since the 1960s, with around 50–100 million people infected yearly. Early descriptions of the condition ...