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Conversely, iron inhibits the uptake of many drugs, such as bisphosphonates, tetracycline antibiotics, quinolone antibiotics, levothyroxin, and levodopa. Combining the drug with intravenous iron can result in fast release of iron into the blood, potentially leading to low blood pressure or even collapse.
Treatment was based on the theory that there is an imbalance of the neurotransmitter dopamine in the basal ganglia. These drugs have fallen out of fashion due to various serious side effects: sedation, parkinsonism, and tardive dyskinesia. [16] Other oral medications can be used in low doses to treat early stages of spasmodic torticollis.
Torticollis is a fixed or dynamic tilt, rotation, with flexion or extension of the head and/or neck. The type of torticollis can be described depending on the positions of the head and neck. [1] [3] [4] laterocollis: the head is tipped toward the shoulder; rotational torticollis: the head rotates along the longitudinal axis towards the shoulder [5]
Common side effects include constipation, abdominal pain, dark stools, and diarrhea. [14] Other side effects, which may occur with excessive use, include iron overload and iron toxicity. [11] [13] Ferrous salts used as supplements by mouth include ferrous fumarate, ferrous gluconate, ferrous succinate, and ferrous sulfate. [13]
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Ferrous sulfate is widely used for both prophylaxis and treatment of iron-deficiency anemia. [23] In 2018, it was the 94th most commonly prescribed drug in the United States, with over eight million prescriptions. [24] Ferrous Sulfate Tablet
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Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine, benztropine, diphenhydramine, and trihexyphenidyl.