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Why Lowering A1C Matters “Diabetes can cause acute life-threatening complications all of which are preventable with good control of A1C,” says Meena Murthy, M.D., chief of the Division of ...
The complications of diabetes can dramatically impair quality of life and cause long-lasting disability. Overall, complications are far less common and less severe in people with well-controlled blood sugar levels. [3] [4] [5] Some non-modifiable risk factors such as age at diabetes onset, type of diabetes, gender, and genetics may influence risk.
Diabetes can cause acute problems such as too low (hypoglycemia) or high blood sugar (hyperglycemia). Diabetes affects the blood vessels in the body, such as capillaries and arteries, which are the routes blood take to deliver nutrients and oxygen to the organs in the body. [ 4 ]
The leading cause of hyperglycemia in type 2 diabetes is the failure of insulin to suppress glucose production by glycolysis and gluconeogenesis due to insulin resistance. [39] Insulin normally inhibits glycogenolysis, but fails to do so in a condition of insulin resistance, resulting in increased glucose production. [ 40 ]
He notes that one of his patients reduced their A1C from 6.2% to 5.8% in just three months by incorporating daily 30-minute walks and twice-weekly strength training.
On the flip side, a diet high in added sugar, refined carbs, and saturated fat increases blood sugar and worsens insulin resistance, in turn, leading to type 2 diabetes, adds Palinski-Wade.
The main aim in the treatment of diabetic ketoacidosis is to replace the lost fluids and electrolytes while suppressing the high blood sugars and ketone production with insulin. Admission to an intensive care unit (ICU) or similar high-dependency area or ward for close observation may be necessary.
Time-restricted eating may improve blood glucose control and help reduce fat when coupled with standard nutritional counseling compared to just the counseling alone, a new study indicates.
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