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  2. Outpatient parenteral antibiotic therapy - Wikipedia

    en.wikipedia.org/wiki/Outpatient_parenteral...

    Outpatient parenteral antibiotic therapy (OPAT) is used to administer non-oral antibiotics (usually intravenously) without the need for ongoing hospitalisation.OPAT is particularly useful for people who are not severely ill but do require a prolonged course of treatment that cannot be given in oral form. [1]

  3. Intrathecal administration - Wikipedia

    en.wikipedia.org/wiki/Intrathecal_administration

    Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF). It is useful in several applications, such as for spinal anesthesia, chemotherapy, or pain management. This route is also used to introduce drugs that fight ...

  4. Volume of distribution - Wikipedia

    en.wikipedia.org/wiki/Volume_of_distribution

    Therefore, the dose required to give a certain plasma concentration can be determined if the V D for that drug is known. The V D is not a physiological value; it is more a reflection of how a drug will distribute throughout the body depending on several physicochemical properties, e.g. solubility, charge, size, etc.

  5. Vancomycin - Wikipedia

    en.wikipedia.org/wiki/Vancomycin

    Vancomycin is a glycopeptide antibiotic medication used to treat certain bacterial infections. [7] It is administered intravenously (injection into a vein) to treat complicated skin infections, bloodstream infections, endocarditis, bone and joint infections, and meningitis caused by methicillin-resistant Staphylococcus aureus. [8]

  6. Glycopeptide antibiotic - Wikipedia

    en.wikipedia.org/wiki/Glycopeptide_antibiotic

    Vancomycin is usually given intravenously, as an infusion, and can cause tissue necrosis and phlebitis at the injection site if given too rapidly. Pain at the site of injection is indeed a common adverse event. One of the side effects is red man syndrome, an idiosyncratic reaction to bolus caused by histamine release.

  7. Injector pen - Wikipedia

    en.wikipedia.org/wiki/Injector_pen

    Injector pens are an alternative to the manufacture of medication for injection in vials containing either liquid or a powder to which a diluent such as sterile water is added. When a vial is used as a means of storage, the end-user must use a syringe to "draw up" or remove the medication from the vial to prepare it for administration.

  8. Anthony Richardson's 2-point conversion run with 12 seconds ...

    www.aol.com/sports/anthony-richardsons-2-point...

    Anthony Richardson scored on a 2-point conversion run up the middle with 12 seconds remaining in the fourth quarter to give the Indianapolis Colts a 25–24 win over the New England Patriots on ...

  9. Loading dose - Wikipedia

    en.wikipedia.org/wiki/Loading_dose

    In pharmacokinetics, a loading dose is an initial higher dose of a drug that may be given at the beginning of a course of treatment before dropping down to a lower maintenance dose. [ 1 ] A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life .