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The American College of Rheumatology recommends colchicine, nonsteroidal anti-inflammatory drugs (NSAIDs) or steroids in the treatment of gout. [8] [9] Other uses for colchicine include the management of pericarditis. [10] Colchicine is taken by mouth. [11] The injectable route of administration for colchicine can be lethal.
Colchicine, which has been essential to treat recurrent pericarditis, has been supported for routine use in acute pericarditis by recent prospective studies. [16] Colchicine can be given 0.6 mg twice a day (0.6 mg daily for patients <70 kg) for 3 months following an acute attack.
The treatment in viral or idiopathic pericarditis is with aspirin, [11] or non-steroidal anti-inflammatory drugs (NSAIDs such as ibuprofen). [4] Colchicine may be added to the above as it decreases the risk of further episodes of pericarditis.
Colchicine has been used effectively to prevent pericarditis, and inflammation that follows surgery of the pericardium. [5] Although no current drug on the market prevents post-pericardiotomy syndrome, colchicine seems to provide an effective and safe way to treat pericarditis by reducing inflammation. [6]
Colchicine (Colcrys) for pericarditis: colchicine is indicated for the treatment and prevention of gout, though it is also generally considered first-line treatment for acute pericarditis, as well as preventing recurrent episodes. Although the exact mechanism of colchicine is not fully understood, its anti-inflammatory effect for pericarditis ...
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Constrictive pericarditis is the main long-term complication of tuberculous pericarditis that requires management. [5] Corticosteroids have long been thought to help reduce the risk of future cardiac complications. [3] [7] Colchicine is a drug thought to reduce the recurrence of constrictive pericarditis, although evidence is limited. [5]
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