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Hirudin is a naturally occurring peptide in the salivary glands of blood-sucking leeches (such as Hirudo medicinalis) that has a blood anticoagulant property. [2] This is essential for the leeches' habit of feeding on blood, since it keeps a host's blood flowing after the worm's initial puncture of the skin.
Medicinal leeches have been found to secrete saliva containing about 60 different proteins. [8] These achieve a wide variety of goals useful to the leech as it feeds, helping to keep the blood in liquid form and increasing blood flow in the affected area.
Once attached to a host, they release anticoagulants to prevent clotting. Then, the leeches extract blood at a rate of up to 0.14 ml/min, consuming 15 ml of blood total. [2] [5] Blood is moved into the digestive system through a series of undulation movements, and leeches can go months without feeding.
Hirudo verbana feeds on blood (hematophagy). During a blood meal, a leech rhythmically contracts its muscles to draw blood from a host animal into the crop for storage. It can consume over five times its own weight in blood in one feeding. Once satiated, a leech detaches from its host.
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Blood-sucking leeches use their anterior suckers to connect to hosts for feeding. Once attached, they use a combination of mucus and suction to stay in place while they inject hirudin into the hosts' blood. In general, blood-feeding leeches are non host-specific, and do little harm to their host, dropping off after consuming a blood meal. Some ...