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The two primary methods are testing for the female pregnancy hormone (human chorionic gonadotropin (hCG)) in blood or urine using a pregnancy test kit, and scanning with ultrasonography. [1] Testing blood for hCG results in the earliest detection of pregnancy. [2] Almost all pregnant women will have a positive urine pregnancy test one week ...
The hormone hCG is produced at high levels by a pregnant woman's placenta, which is why it is used to depict positive results for these kinds of tests. At the Test Site, the trapped hCG is sandwiched in between a fixed antibody with a dye substrate, resulting in the first line of the pregnancy test appearing.
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The term "rabbit test" was first recorded in 1949, and was the origin of a common euphemism, "the rabbit died", for a positive pregnancy test. [4] The phrase was, in fact, based on a common misconception about the test. While many people assumed that the injected rabbit would die only if the woman was pregnant, in fact all rabbits used for the ...
Human chorionic gonadotropin is a glycoprotein composed of 237 amino acids with a molecular mass of 36.7 kDa, approximately 14.5kDa αhCG and 22.2kDa βhCG. [4]It is heterodimeric, with an α (alpha) subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and a β (beta) subunit that is unique to hCG.
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The hCG test can be used to screen for uterus cancer, or a molar pregnancy, which is when there is abnormal placental growth in the uterus. [9] The hCG test can also be done after a miscarriage to ensure that a molar pregnancy is not present. In men, the hCG test can be used to screen for the presence of testicular cancer. [9]
Margaret Crane's patent illustration for "Diagnostic Test Device", the first home pregnancy test. Margaret M. Crane (Meg Crane) is an American inventor and graphic designer who created the first at home pregnancy test in 1967 while working at Organon Pharmaceuticals in West Orange, New Jersey. [1]