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  2. Tizanidine - Wikipedia

    en.wikipedia.org/wiki/Tizanidine

    Tizanidine, sold under the brand name Zanaflex among others, is an alpha-2 (α 2) adrenergic receptor agonist, [2] similar to clonidine, that is used to treat muscle spasticity due to spinal cord injury, multiple sclerosis, and spastic cerebral palsy. [3] Effectiveness appears similar to baclofen or diazepam. [4] It is taken by mouth. [5]

  3. Muscle relaxant - Wikipedia

    en.wikipedia.org/wiki/Muscle_relaxant

    [27] [28] Furthermore, several clinical trials indicate that tizanidine has a similar efficacy to other spasmolytic agents, such as diazepam and baclofen, with a different spectrum of adverse effects. [29] The hydantoin derivative dantrolene is a spasmolytic agent with a unique mechanism of action outside of the CNS.

  4. Benzodiazepine - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine

    Baclofen [65] or tizanidine are sometimes used as an alternative to benzodiazepines. Tizanidine has been found to have superior tolerability compared to diazepam and baclofen. [66] Benzodiazepines are also used to treat the acute panic caused by hallucinogen intoxication. [67]

  5. Antispasmodic - Wikipedia

    en.wikipedia.org/wiki/Antispasmodic

    Another class of antispasmodics for such treatment includes cyclobenzaprine, carisoprodol, diazepam, orphenadrine, and tizanidine. [7] Meprobamate is another effective antispasmodic which was first introduced for clinical usage in 1955 mainly as an anxiolytic and soon afterward became a blockbuster psychotropic drug.

  6. Baclofen - Wikipedia

    en.wikipedia.org/wiki/Baclofen

    Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [ 8 ] [ 9 ] It may also be used for hiccups and muscle spasms near the end of life, [ 9 ] and off-label to treat alcohol use disorder [ 10 ] [ 11 ] or opioid withdrawal symptoms. [ 12 ]

  7. Hereditary spastic paraplegia - Wikipedia

    en.wikipedia.org/wiki/Hereditary_spastic_paraplegia

    Baclofen – a voluntary muscle relaxant to relax muscles and reduce tone. This can be administered orally or intrathecally. (Studies in HSP [22] [23] [24]) Tizanidine – to treat nocturnal or intermittent spasms (studies available [25] [26]) Diazepam and clonazepam – to decrease intensity of spasms [citation needed]

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    Enjoy a classic game of Hearts and watch out for the Queen of Spades!

  9. Spasticity - Wikipedia

    en.wikipedia.org/wiki/Spasticity

    Spasticity is often treated with the drug baclofen, which acts as an agonist at GABA receptors, which are inhibitory. Spastic cerebral palsy is the most common form of cerebral palsy, which is a group of permanent movement problems that do not get worse over time. GABA's inhibitory actions contribute to baclofen's efficacy as an anti-spasticity ...

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