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  2. Chronic eosinophilic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_eosinophilic_leukemia

    Signs and symptoms may include weight loss, fever, malaise, cough, skin and mucosal lesions, diarrhea, and peripheral neuropathy. Cardiac symptoms are also possible. [2] In cases associated with PDGFRB and FGFR1 mutations, splenomegaly is common. Lymphadenopathy is also common with FGFR1 mutations. [2] Infiltration of eosinophils causes organ ...

  3. Eosinophilia - Wikipedia

    en.wikipedia.org/wiki/Eosinophilia

    Eosinophilia is a condition in which the eosinophil count in the peripheral blood exceeds 5 × 10 8 /L (500/μL). [1] Hypereosinophilia is an elevation in an individual's circulating blood eosinophil count above 1.5 × 10 9 /L (i.e. 1,500/μL).

  4. Acute eosinophilic leukemia - Wikipedia

    en.wikipedia.org/wiki/Acute_eosinophilic_leukemia

    Patients with acute eosinophilic leukemia have a propensity for developing bronchospasm as well as symptoms of the acute coronary syndrome and/or heart failure due to eosinophilic myocarditis and eosinophil-based endomyocardial fibrosis. [1] [2] Hepatomegaly and splenomegaly are more common than in other variants of AML.

  5. Hypereosinophilic syndrome - Wikipedia

    en.wikipedia.org/wiki/Hypereosinophilic_syndrome

    Depending on eosinophil target-organ infiltration, the clinical presentation of hypereosinophilic syndrome (HES) varies from patient to patient. [13] Individuals with myeloproliferative variant HES may be more likely to experience mucosal ulcerations involving the genitalia or airways, while patients with lymphocytic variant HES typically exhibit prominent skin symptoms such as urticarial ...

  6. Leukocytosis - Wikipedia

    en.wikipedia.org/wiki/Leukocytosis

    Leukocytosis can be subcategorized by the type of white blood cell that is increased in number. Leukocytosis in which neutrophils are elevated is neutrophilia; leukocytosis in which lymphocyte count is elevated is lymphocytosis; leukocytosis in which monocyte count is elevated is monocytosis; and leukocytosis in which eosinophil count is elevated is eosinophilia.

  7. Lymphocyte-variant hypereosinophilia - Wikipedia

    en.wikipedia.org/wiki/Lymphocyte-variant_hyper...

    Criteria for the diagnosis include findings of: a) long term hypereosinophilia (i.e. eosinophil blood counts >1,500/microliter) plus physical findings and symptoms associated with the disease; b) bone marrow analysis showing abnormally high levels of eosinophils; c) elevated serum levels of Immunoglobulin E, other immunoglobulins, and CCL17; d ...

  8. Clonal hypereosinophilia - Wikipedia

    en.wikipedia.org/wiki/Clonal_hypereosinophilia

    For example, eosinophilia occurs in 20% to 30% of patients with systemic mastocytosis. Also referred to as SM-eo (systemic mastocytosis with eosinophilia) or SM-SEL (systemic mastocytosis with chronic eosinophilic leukemia), this disease's clonal eosinophils bear the same driving mutation, D816V in the KIT gene, as the clonal mast cells. [1] [32]

  9. Eosinophilic leukemia - Wikipedia

    en.wikipedia.org/wiki/Eosinophilic_leukemia

    Types of eosinophilic leukemia include: Chronic eosinophilic leukemia; Acute eosinophilic leukemia; Clonal eosinophilia This page was last edited on 11 May 2022, at ...

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