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Gastritis is the inflammation of the lining of the stomach. [1] It may occur as a short episode or may be of a long duration . [ 1 ] There may be no symptoms but, when symptoms are present, the most common is upper abdominal pain (see dyspepsia ). [ 1 ]
Atrophic gastritis under low power. H&E stain. Autoimmune metaplastic atrophic gastritis (AMAG) is an inherited form of atrophic gastritis characterized by an immune response directed toward parietal cells and intrinsic factor. [6] Achlorhydria induces G cell (gastrin-producing) hyperplasia, which leads to hypergastrinemia.
Reactive gastropathy, chemical gastropathy also called gastritis of « C type » or "chemical gastritis" [1] is an abnormality in the stomach caused by chemicals, e.g. bile, alcohol, and characteristically has minimal inflammation.
Stomach diseases include gastritis, gastroparesis, Crohn's disease and various cancers. [1] The stomach is an important organ in the body. It plays a vital role in digestion of foods, releases various enzymes and also protects the lower intestine from harmful organisms. The stomach connects to the esophagus above and to the small intestine below.
Inflammation of the stomach by infection from any cause is called gastritis, and when including other parts of the gastrointestinal tract called gastroenteritis. When gastritis persists in a chronic state, it is associated with several diseases, including atrophic gastritis, pyloric stenosis, and gastric cancer.
Organic indigestion is the result of an underlying disease, such as gastritis, peptic ulcer disease (an ulcer of the stomach or duodenum), or cancer. [6] Functional indigestion (previously called non-ulcer dyspepsia) [7] is indigestion without evidence of underlying disease. [8]
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A greater cytotoxicity will result in the change from a non-atrophic gastritis to an atrophic gastritis, with the loss of mucous glands. This condition is a prequel to the development of peptic ulcers and gastric adenocarcinoma.
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