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Celecoxib, sold under the brand name Celebrex among others, is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID). [7] It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. [7]
In the CLASS trial which compared Celebrex 800 mg/day to ibuprofen 2400 mg/day and diclofenac 150 mg/day for osteoarthritis or rheumatoid arthritis for six months, Celebrex was associated with significantly fewer upper gastrointestinal complications (0.44% vs. 1.27%, p = 0.04), with no significant difference in incidence of cardiovascular ...
Duloxetine, sold under the brand name Cymbalta among others, [1] is a medication used to treat major depressive disorder, generalized anxiety disorder, obsessive-compulsive disorder, fibromyalgia, neuropathic pain and central sensitization. [10] [11] It is taken by mouth. [10] Duloxetine is a serotonin–norepinephrine reuptake inhibitor (SNRI ...
Duloxetine (Cymbalta) Milnacipran (Savella) Levomilnacipran (Fetzima) SNRIs (serotonin-norepinephrine reuptake inhibitors) are also responsible for increasing serotonin levels. They double up by ...
The U.S. Food and Drug Administration announced late Thursday it has approved expanding the use of Eli Lilly's blockbuster antidepressant Cymbalta to treat chronic musculoskeletal pain, such as ...
Cymbalta is primarily used to treat GAD and MDD, but it can also help with neuropathic pain. Effexor, on the other hand, is most known for treating major depression, social anxiety disorder ...
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