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Betamethasone belongs to the glucocorticoid class of medication. [3] It is a stereoisomer of dexamethasone, the two compounds differing only in the spatial configuration of the methyl group at position 16 (see steroid nomenclature). [5] Betamethasone was patented in 1958, and approved for medical use in the United States in 1961.
Antenatal steroids have also been shown to have definite beneficial effect in treating the condition of preterm premature rupture of membranes (PPROM). [8] Similar to its effects on preterm birth, research evidence suggests that the administration of antenatal steroids to patients with PPROM reduces risks of neonatal mortality, intraventricular hemorrhage and respiratory distress syndrome.
The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk .
The methasones (or metasones) are a class of corticosteroids [1] which are generally used in dermatology.They are defined by substitution with a methyl group at the C16α or C16β position of the pregnane steroid nucleus.
Betamethasone has also been used in the formulation of combination products such as Luxiq, Lotrisone and Taclonex. Prestium Pharma: Luxiq (betamethasone valerate) Foam, 0.12% [11] is a mid-strength corticosteroid foam used primarily to treat psoriasis or other inflammatory conditions of the scalp.
Hydrops Fetalis resulting from fetal CPAM can be treated using either a fetal needle drainage of effusion or placement of thoracoamniotic shunt or a maternal administration of corticosteroids, betamethasone 12.5 mg IM q24 h × 2 doses or dexamethasone 6.25 mg IM q12 h × 4 doses. [15]
Betamethasone sodium phosphate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. [1] It is the di sodium salt of the phosphate ester of betamethasone . See also
Tocolytics are used in preterm labor, which refers to when a baby is born too early before 37 weeks of pregnancy. As preterm birth represents one of the leading causes of neonatal morbidity and mortality, the goal is to prevent neonatal morbidity and mortality through delaying delivery and increasing gestational age by gaining more time for other management strategies like corticosteroids ...