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2. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

   www.aol.com/tadalafil-ultimate-guide-dosages...

   That’s a really long time — and it’s only an average. ... Clinical trials show that side effects from tadalafil are slightly more common at this dosage than at a lower dosage of 10mg, though ...

3. Is It Safe to Take Cialis Daily? - AOL

   www.aol.com/safe-cialis-daily-115900442.html

   Cialis can take three to five days to reach its peak concentration. ... may cause some unwanted side effects to occur for a longer period of time. ... and generic tadalafil can cause side effects ...

4. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

   www.aol.com/cialis-side-effects-expect-avoid...

   Remember, tadalafil 5-milligram side effects tend to be less severe than those experienced with 10- or 20-milligram dosages. Your provider may recommend adjusting your Cialis dosage if you’re ...

5. Tadalafil - Wikipedia

   en.wikipedia.org/wiki/Tadalafil

   A meta‐analysis found that tadalafil is an effective treatment for lower urinary tract symptoms due to benign prostatic hyperplasia and that such treatment had a low rate of adverse effects. [12] Tadalafil is FDA-approved for males as a therapy to treat and prevent symptoms of benign prostatic hyperplasia, such as urinary urgency, hesitancy ...

6. Area under the curve (pharmacokinetics) - Wikipedia

   en.wikipedia.org/wiki/Area_under_the_curve...

   The area under the effect curve (AUEC) is an integral of the effect of a drug over time, estimated as a previously-established function of concentration. It was proposed to be used instead of AUC in animal-to-human dose translation, as computer simulation shows that it could cope better with half-life and dosing schedule variations than AUC.

7. Onset of action - Wikipedia

   en.wikipedia.org/wiki/Onset_of_action

   A few drugs such as alcohol are absorbed by the lining of the stomach, and therefore tend to take effect much more quickly than the vast majority of oral medications which are absorbed in the small intestine. Gastric emptying time can vary from 0 to 3 hours, [2] and therefore plays a major role in onset of action for orally administered drugs ...