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Influencers such as Peter Attia, MD are currently taking the drug “off label” for its anti-aging potential. Attia said that rapamycin, “hands down [is] the most important and exciting and ...
Peter Attia (born March 19, 1973) [1] is a Canadian-American author, physician, and researcher known for his work in longevity medicine. Early life and education [ edit ]
mTOR inhibitors are a class of drugs used to treat several human diseases, including cancer, autoimmune diseases, and neurodegeneration. They function by inhibiting the mammalian target of rapamycin (mTOR) (also known as the mechanistic target of rapamycin), which is a serine/threonine-specific protein kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K) related kinases ...
Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumour (PEComa).
Temsirolimus is a specific inhibitor of mTOR and interferes with the synthesis of proteins that regulate proliferation, growth, and survival of tumor cells. Though temsirolimus shows activity on its own, it is also known to be converted to sirolimus (rapamycin) in vivo; [4] therefore, its activity may be more attributed to its metabolite rather than the prodrug itself (despite claims to the ...
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Enjoy a month of Mediterranean diet dinner recipes featuring high-fiber whole grains, nutrient-rich veggies, lean proteins and heart-healthy fats.
Torin_1 is a drug which was one of the first non-rapalog derived inhibitors of the mechanistic target of rapamycin ...