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Healthy people may not have many symptoms with methemoglobin levels below 15%. However, people with co-morbidities such as anemia , cardiovascular disease, lung disease, sepsis , or who have abnormal hemoglobin species (e.g. carboxyhemoglobin , sulfhemoglobinemia or sickle hemoglobin ) may experience moderate to severe symptoms at much lower ...
The structure of cytochrome b5 reductase, the enzyme that converts methemoglobin to hemoglobin. [1]Methemoglobin (British: methaemoglobin, shortened MetHb) (pronounced "met-hemoglobin") is a hemoglobin in the form of metalloprotein, in which the iron in the heme group is in the Fe 3+ state, not the Fe 2+ of normal hemoglobin.
The Fugates, commonly known as the "Blue Fugates" [1] or the "Blue People of Kentucky", are an ancestral family living in the hills of Kentucky starting in the 19th century, where they are known for having a genetic trait that led to the blood disorder methemoglobinemia, causing the skin to appear blue.
Cyanide binds avidly to methemoglobin, forming cyanmethemoglobin, thus releasing cyanide from cytochrome oxidase. [38] Treatment with nitrites is not innocuous as methemoglobin cannot carry oxygen, and severe methemoglobinemia may need to be treated in turn with methylene blue. [note 1] Thiosulfate
The increase in people living with cancer by December 2025 includes about 890,000 women with breast cancer, 610,000 men with prostate cancer, 390,000 people with bowel cancer and 120,000 people ...
In an age where convenience often trumps nutritional value, a growing body of research is raising concerns about the health implications of eating ultra-processed foods.These foods undergo ...
Why the meat you eat affects your brain. The connection between red meat and cognitive health hasn’t been studied thoroughly, but researchers have found associations with many other health ...
Methylthioninium chloride, commonly called methylene blue, is a salt used as a dye and as a medication. As a medication, it is mainly used to treat methemoglobinemia by chemically reducing the ferric iron in hemoglobin to ferrous iron.