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  2. Active metabolite - Wikipedia

    en.wikipedia.org/wiki/Active_metabolite

    An active metabolite results when a drug is metabolized by the body into a modified form which produces effects in the body. Usually these effects are similar to those of the parent drug but weaker, [citation needed] although they can still be significant (see e.g. 11-hydroxy-THC, morphine-6-glucuronide).

  3. Metabolite - Wikipedia

    en.wikipedia.org/wiki/Metabolite

    In biochemistry, a metabolite is an intermediate or end product of metabolism. [1] The term is usually used for small molecules.Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, catalytic activity of their own (usually as a cofactor to an enzyme), defense, and interactions with other organisms (e.g. pigments, odorants, and ...

  4. Category:Human metabolites - Wikipedia

    en.wikipedia.org/wiki/Category:Human_metabolites

    Pages in category "Human metabolites" The following 89 pages are in this category, out of 89 total. This list may not reflect recent changes. A. Adrenaline;

  5. Category:Human drug metabolites - Wikipedia

    en.wikipedia.org/.../Category:Human_drug_metabolites

    Pages in category "Human drug metabolites" The following 188 pages are in this category, out of 188 total. This list may not reflect recent changes. 0–9. 4-HO-TMT;

  6. List of benzodiazepines - Wikipedia

    en.wikipedia.org/wiki/List_of_benzodiazepines

    Some benzodiazepines produce active metabolites. Active metabolites are produced when a person's body metabolizes the drug into compounds that share a similar pharmacological profile to the parent compound and thus are relevant when calculating how long the pharmacological effects of a drug will last.

  7. Metabolism - Wikipedia

    en.wikipedia.org/wiki/Metabolism

    Metabolism (/ m ə ˈ t æ b ə l ɪ z ə m /, from Greek: μεταβολή metabolē, "change") is the set of life-sustaining chemical reactions in organisms.The three main functions of metabolism are: the conversion of the energy in food to energy available to run cellular processes; the conversion of food to building blocks of proteins, lipids, nucleic acids, and some carbohydrates; and the ...

  8. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    1576 n/a Ensembl ENSG00000160868 n/a UniProt P08684 n/a RefSeq (mRNA) NM_001202855 NM_001202856 NM_001202857 NM_017460 n/a RefSeq (protein) NP_001189784 NP_059488 n/a Location (UCSC) Chr 7: 99.76 – 99.78 Mb n/a PubMed search n/a Wikidata View/Edit Human Cytochrome P450 3A4 (abbreviated CYP3A4) (EC 1.14.13.97) is an important enzyme in the body, mainly found in the liver and in the intestine ...

  9. Cytochrome P450 (individual enzymes) - Wikipedia

    en.wikipedia.org/wiki/Cytochrome_P450...

    P450s are the major enzymes involved in drug metabolism, accounting for about 75% of the total metabolism. [7] Most drugs undergo deactivation by P450s, either directly or by facilitated excretion from the body. However, many substances are bioactivated by P450s to form their active compounds like the antiplatelet drug clopidogrel and the ...