Search results
Results from the WOW.Com Content Network
Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative.It is a first-generation H 1-antihistamine and it works by blocking certain effects of histamine, which produces its antihistamine and sedative effects.
Some forms of Benadryl are to be taken orally, while some creams and gels are to be applied to the skin. [2] Common side effects of the drug include drowsiness, dizziness, dry mouth and throat, confusion, and blurred vision. [2] In the United States and Canada, the active ingredient is diphenhydramine.
Piperoxan was discovered in 1933 and was the first compound with antihistamine effects to be identified. [22] Piperoxan and its analogues were too toxic to be used in humans. [22] Phenbenzamine (Antergan) was the first clinically useful antihistamine and was introduced for medical use in 1942. [22]
The recommended dosage of Benadryl tablets for adults is 1 to 2 tablets every 4 to 6 hours, [1] and only 1 tablet every 4 to 6 hours for children under the age of 12. [2]The Benadryl challenge is an internet challenge that emerged in 2020, revolving around the deliberate consumption, excessive use and overdose of the antihistamine medicine diphenhydramine (commonly sold in the United States ...
First-generation antihistamines include diphenhydramine (Benadryl), carbinoxamine (Clistin), clemastine (Tavist), chlorpheniramine (Chlor-Trimeton), and brompheniramine (Dimetane). However, a 1955 study of "antihistaminic drugs for colds," carried out by the U.S. Army Medical Corps, reported that "there was no significant difference in the ...
Diphenhydramine is the primary constituent of dimenhydrinate and dictates the primary effect. The main differences relative to pure diphenhydramine are a lower potency due to being combined with 8-chlorotheophylline (by weight, dimenhydrinate is between 53% and 55.5% diphenhydramine) [10] and the fact that the stimulant properties of 8-chlorotheophylline help reduce the side ...
An action spectrum is a graph of the rate of biological effectiveness plotted against wavelength of light. [1] It is related to absorption spectrum in many systems. Mathematically, it describes the inverse quantity of light required to evoke a constant response.
The Drug Effectiveness Review Project (DERP) is a self-governed collaboration of state Medicaid and public pharmacy programs that commission high-quality evidence-based research products to assist policymakers and other decision-makers grappling with difficult drug coverage decisions.