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The precise mechanism for its antidepressant and anxiolytic effects is not known. [10] Common side effects include dry mouth, nausea, feeling tired, dizziness, agitation, sexual problems, and increased sweating. [10] Severe side effects include an increased risk of suicide, serotonin syndrome, mania, and liver problems. [10]
To cross-taper, you’ll need to gradually reduce the dosage of your old antidepressant while gradually increasing the dosage of your new medication at the same time. This technique may be used if ...
Increasing the electron-withdrawing nature of the aromatic ring provides a more potent inhibitory effect of norepinephrine uptake and improves the selectivity for norepinephrine over the serotonin transporter. [36] Effects of chloro, methoxy and trifluoromethyl substituents in the aromatic ring of cycloalkanol ethylamine scaffold were tested.
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.
The Food and Drug Administration has announced a recall for thousands of bottles of the antidepressant duloxetine, sold under brand names like Cymbalta, due to the presence of a chemical that can ...
Antidepressants can include SSRIs (which increase serotonin levels in the brain), SNRIs (which increase serotonin and norepinephrine), and atypical antidepressants (Wellbutrin, for example), along ...
A 2005 meta-analysis of drug company data found no evidence that SSRIs increased the risk of suicide; however, important protective or hazardous effects could not be excluded. [ 134 ] A 2005 review observed that suicide attempts are increased in those who use SSRIs as compared to placebo and compared to therapeutic interventions other than ...
The drug is sold under the brand name Cymbalta. The Duloxetine Delayed-Release Capsules' voluntary recall began on Oct. 10 after the FDA deemed the medication the second-highest risk classification.