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In a clinical trial involving human subjects, a set of content known as a trial master file (TMF) must be produced in accordance with applicable international and local regulations. TMFs are a collection of documents and other artifacts which "individually and collectively permit evaluation of the conduct of a trial and the quality of the data ...
An electronic trial master file (eTMF) is a trial master file in electronic (digital content) format.It is a type of content management system for the pharmaceutical industry, providing a formalized means of organizing and storing documents, images, and other digital content for pharmaceutical clinical trials that may be required for compliance with government regulatory agencies.
A case report form (or CRF) is a paper or electronic questionnaire specifically used in clinical trial research. [1] The case report form is the tool used by the sponsor of the clinical trial to collect data from each participating patient.
2,2,5,5-tetramethyltetrahydrofuran (TMTHF) or 2,2,5,5-tetramethyloxolane (TMO) is a heterocyclic compound with the formula C 8 H 16 O, or (CH 3) 2 (C(CH 2) 2 OC)(CH 3) 2.It can be seen as derivative of tetrahydrofuran (oxolane) with four methyl groups replacing four hydrogen atoms on each of the carbon atoms in the ring that are adjacent to the oxygen.
In software development, a traceability matrix (TM) [1]: 244 is a document, usually in the form of a table, used to assist in determining the completeness of a relationship by correlating any two baselined documents using a many-to-many relationship comparison.
Tracing in software engineering refers to the process of capturing and recording information about the execution of a software program. This information is typically used by programmers for debugging purposes, and additionally, depending on the type and detail of information contained in a trace log, by experienced system administrators or technical-support personnel and by software monitoring ...
(h 3 o)tm 3 f 10 → 3 tmf 3 + hf↑ + h 2 o↑ Thulium(III) oxide reacts with fluorinating agents such as hydrogen fluoride , [ 2 ] nitrogen trifluoride [ 3 ] xenon difluoride [ 4 ] to create thullium(III) fluoride as well, although the reaction with nitrogen trifluoride is incomplete and produces a mixture of TmOF and TmF 3 .
Tetramethylammonium fluoride, commonly abbreviated TMAF, is the quaternary ammonium salt with the formula (CH 3) 4 NF. This hygroscopic white solid is a source of “naked fluoride": fluoride ions not complexed with a metal atom.