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CBD has crossed over from the world of alternative wellness into the mainstream. Thanks to its many benefits (like bringing about feelings of calm and pain relief) and lack of psychoactive effects ...
[17] [25] [27] [28] Conversion of CBD to THC can occur when CBD is heated to temperatures between 250–300 °C, potentially leading to its partial transformation into THC. [29] In the United States, the cannabidiol drug Epidiolex was approved by the Food and Drug Administration (FDA) in 2018 for the treatment of two seizure disorders. [4]
CBD heated to 175, [13] or 250–300 °C may partially be converted into THC. [14] Even at room temperature, trace amounts of THC can be formed as a contaminant in CBD stored for long periods in the presence of moisture and carbon dioxide in the air, with storage under inert gas required to maintain analytically pure CBD.
The use of THC in any capacity may lead to health concerns and users should consult medical personnel before consumption. Local and state laws for use and possession of THC vary by jurisdiction ...
Conflicting reports but generally described as negative allosteric modulator at CB1 & CB2, altering THC activity when THC & CBD are coadministered [16] Agonist at TRPA1, [ 13 ] TRPV1 (high potency at this “capsaicin receptor” without ablative effects [ 13 ] ), TRPV2, TRPV3, PPARγ, 5-HT1A, A2 and A1 adenosine receptors [ 16 ]
The product pages for both Gentle Wave and Vigorvita CBD Gummies are both registered to an address in Reykjavik, Iceland, and calls to the registrant’s Iceland phone number were not answered.
A review of literature up to 2018 indicates that cannabidiol (CBD) may have therapeutic potential for the treatment of insomnia. CBD, a non-psychoactive component of cannabis, is of particular interest due to its potential to influence sleep without the psychoactive effects associated with tetrahydrocannabinol (THC). [24]
CBD shares a precursor with THC and is the main cannabinoid in CBD-dominant Cannabis strains. CBD has been shown to play a role in preventing the short-term memory loss associated with THC. [29] There is tentative evidence that CBD has an anti-psychotic effect, but research in this area is limited. [30] [24]