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The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...
The Oxford Textbook of Medicine [1] is an international textbook of medicine.First published in 1983, the sixth edition was released in 2020. [2] It is primarily aimed at mature physicians looking for information outside their area of particular expertise, but widely used as a reference source by medical students and doctors in training, and by others seeking authoritative accounts of the ...
The first edition of The Merck Manual was published in 1899 by Merck & Co., Inc. for physicians and pharmacists and was titled Merck's Manual of the Materia Medica. [6] [7] The 192 page book which sold for US $1.00, was divided into three sections, Part I ("Materia Medica") was an alphabetical listing of all known compounds thought to be of therapeutic value with uses and doses; Part II ...
Goldberg discussing his new book with Mark Leyner in New York City, August 2006. Billy Goldberg (born April 10, 1966) is a New York City emergency medicine physician at the NYU School of Medicine (Bellevue Hospital and New York University (NYU) Medical Center), where he is also an Assistant Professor and an Assistant Director in the Department of Emergency Medicine. [1]
Book of Optics (c. 1000) - Exerted great influence on Western science. [16] It was translated into Latin and it was used until the early 17th century. [ 17 ] The German physician Hermann von Helmholtz reproduced several theories of visual perception that were found in the first Book of Optics , which he cited and copied from.
It is distinct from dose, which denotes a single, specific quantity of a drug or substance given at one time. [2] Dosage typically includes information on the number of doses, intervals between administrations, and the overall treatment period. [ 3 ]
Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects. [ 1 ] When a drug has a narrow therapeutic index , titration is especially important, because the range between the dose at which a drug is effective and the dose at which side effects occur is small. [ 2 ]
In pharmacokinetics, a loading dose is an initial higher dose of a drug that may be given at the beginning of a course of treatment before dropping down to a lower maintenance dose. [ 1 ] A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life .