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In acute medicine, midazolam has become more popular than other benzodiazepines, such as lorazepam and diazepam, because it is shorter lasting, is more potent, and causes less pain at the injection site. [69] Midazolam is also becoming increasingly popular in veterinary medicine due to its water solubility. [75]
Glossip v. Gross, 576 U.S. 863 (2015), was a United States Supreme Court case in which the Court held, 5–4, that lethal injections using midazolam to kill prisoners convicted of capital crimes do not constitute cruel and unusual punishment under the Eighth Amendment to the United States Constitution. The Court found that condemned prisoners ...
In 2021, following a series of legal challenges to lethal injection, executions resumed in the state, starting with Grant. His execution generated significant media attention and controversy due to his negative reaction to the lethal injection drugs, particularly the sedative midazolam.
Lethal injection is the practice of injecting one or more drugs into a person (typically a barbiturate, paralytic, and potassium solution) for the express purpose of causing rapid death. The main application for this procedure is capital punishment, but the term may also be applied in a broader sense to include euthanasia and other forms of ...
Among all benzodiazepine agents, midazolam (Versed) is the most frequently used medication for palliative sedation for its rapid onset and short duration of action. The main indications for midazolam in palliative sedation are to control delirium and alleviate breathing difficulties so as to minimize distress and prevent exacerbation of these ...
Midazolam is the most commonly prescribed for this use because of its strong sedative actions and fast recovery time, as well as its water solubility, which reduces pain upon injection. Diazepam and lorazepam are sometimes used. Lorazepam has particularly marked amnesic properties that may make it more effective when amnesia is the desired effect.
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[35] [36] In 2015, Frazier was one of five death row prisoners who filed a lawsuit opposing the state authorities' bid to administer large doses of midazolam in lethal injection executions. [37] [38] Subsequently, by 2018, the lawmakers of Alabama managed to legalize executions by nitrogen hypoxia as an alternative method of execution in the state.
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