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The Biopython project is an open-source collection of non-commercial Python tools for computational biology and bioinformatics, created by an international association of developers. [ 1 ] [ 4 ] [ 5 ] It contains classes to represent biological sequences and sequence annotations , and it is able to read and write to a variety of file formats.
Computational biology is a specialized domain that often requires knowledge of computer programming. Galaxy aims to give biomedical researchers access to computational biology without also requiring them to understand computer programming. [13] [14] Galaxy does this by stressing a simple user interface [15] over the ability to build complex ...
Open Bioinformatics Foundation: Biopython: Python language toolkit Cross-platform: Biopython [2] Open Bioinformatics Foundation: BioRuby: Ruby language toolkit Linux, macOS, Windows [3] GPL v2 or Ruby: Open Bioinformatics Foundation: BLAST: Algorithm and program for comparing primary biological sequence information, including DNA and protein ...
Python tool for modeling and analyzing SBML models [21] [22] [23] multiplatform (Python) BSD-3: Yes pySB: Python-based [24] platform with specialization in rule-based models. multiplatform (Python) BSD-3: Partial ReaDDy: Particle-based spatial simulator with intermolecular potentials [25] Linux and Mac: Custom: Not applicable SBSCL
Predict the minimum free energy structure of nucleic acids. seqfold is an implementation of the Zuker, 1981 dynamic programming algorithm, the basis for UNAFold/mfold, with energy functions from SantaLucia, 2004 (DNA) and Turner, 2009 (RNA). MIT license. Python CLI or module. No: link & source [30] Sfold: Statistical sampling of all possible ...
Originally developed in MATLAB, [14] it was re-written in Python and released as CellProfiler 2.0 in 2010. [2] Version 3.0, supporting volumetric analysis of 3D image stacks and optional deep learning modules, was released in October 2017. [16]
In bioinformatics, MAFFT (multiple alignment using fast Fourier transform) is a program used to create multiple sequence alignments of amino acid or nucleotide sequences. Published in 2002, the first version used an algorithm based on progressive alignment, in which the sequences were clustered with the help of the fast Fourier transform. [2]
pyOpenMS is an open-source Python library for mass spectrometry, specifically for the analysis of proteomics and metabolomics data in Python. Peaksel Proprietary: This web-based (available both in cloud as SaaS and as on-prem installation) software for LC/MS data processing supports batch processing and high-throughput experiments.