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Intrahepatic cholestasis of pregnancy (ICP), also known as obstetric cholestasis, cholestasis of pregnancy, jaundice of pregnancy, and prurigo gravidarum, [1] is a medical condition in which cholestasis occurs during pregnancy. [2] It typically presents with itching and can lead to complications for both mother and fetus. [2]
Cholestatic pruritus is the sensation of itch due to nearly any liver disease, but the most commonly associated entities are primary biliary cholangitis, primary sclerosing cholangitis, obstructive choledocholithiasis, carcinoma of the bile duct, cholestasis (also see drug-induced pruritus), and chronic hepatitis C viral infection and other forms of viral hepatitis.
PUPPP most commonly presents as a rash that starts within the stretch marks. This rash may then move to other areas of the body, including, but not limited to the trunk of the body, arms, legs, feet, chest, and neck. Very few people experiencing PUPPP have reported the rash spreading to the face, palms of hands, or soles of feet. [3] [6]
Cholestasis is a condition where the flow of bile from the liver to the duodenum is impaired. [1] The two basic distinctions are: [1] obstructive type of cholestasis, where there is a mechanical blockage in the duct system that can occur from a gallstone or malignancy, and
The signs and symptoms of pruritic folliculitis of pregnancy include: redness of the skin, small red bumps that surrounds a hair follicle, and red bumps that are filled with pus "that usually appear first on the abdomen and may spread to the chest, upper portion of the back, shoulders, arms, and thighs" and it occurs during the second or third ...
Pregnancy-related cutaneous conditions are a group of skin changes observed during pregnancy. ... Intrahepatic cholestasis of pregnancy; J. ... Toxemic rash of pregnancy;
The exact etiology is unknown, but it is considered likely to be a flareup of atopic dermatitis during pregnancy. [6] It is sometimes considered to be a term encompassing Besnier's prurigo gestationis and other conditions. [7] It is sometimes considered a diagnosis of exclusion. [8]
Pregnancy-related cutaneous conditions are a group of skin changes observed during pregnancy. [93] [94] Impetigo herpetiformis; Intrahepatic cholestasis of pregnancy (cholestasis of pregnancy, jaundice of pregnancy, obstetric cholestasis, prurigo gravidarum) Linea nigra; Pemphigoid gestationis (gestational pemphigoid, herpes gestationis)