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Denervation is any loss of nerve supply regardless of the cause. If the nerves lost to denervation are part of neural communication to an organ system or for a specific tissue function, alterations to or compromise of physiological functioning can occur. [ 1 ]
Dopamine dysregulation syndrome (DDS) is a dysfunction of the reward system observed in some individuals taking dopaminergic medications for an extended length of time. It is characterized by severely disinhibited patterns of behavior, [1] leading to problems such as addiction to the offending medication, gambling addiction, or compulsive sexual behavior, [2] along with a general orientation ...
Complex regional pain syndrome is uncommon, and its cause is not clearly understood. CRPS typically develops after an injury, surgery, heart attack, or stroke. [ 8 ] [ 12 ] Investigators estimate that 2–5% of those with peripheral nerve injury, [ 13 ] and 13–70% of those with hemiplegia (paralysis of one side of the body) [ 14 ] will ...
For four years it only ever showed denervation in my left leg, nowhere else. In March 2022, they saw it in my right leg too — an official sign of progression. They checked my arm and saw it was ...
Disuse supersensitivity, also pharmacological disuse supersensitivity or pharmacological denervation supersensitivity, is the increased sensitivity by a postsynaptic cell because of decreased input by incoming axons, e.g., due to the exposure to an antagonist drug.
Diabetes is the foremost cause in America today for neuropathic joint disease, [5] and the foot is the most affected region. In those with foot deformity, approximately 60% are in the tarsometatarsal joints (medial joints affected more than lateral), 30% metatarsophalangeal joints, and 10% have ankle disease. Over half of diabetic patients with ...
Neurolysis is the application of physical or chemical agents to a nerve in order to cause a temporary degeneration of targeted nerve fibers. When the nerve fibers degenerate, it causes an interruption in the transmission of nerve signals. In the medical field, this is most commonly and advantageously used to alleviate pain in cancer patients. [1]
Joint pain is a common symptom we all experience at some point or another. Painful joints can have a significant impact on quality of life and the ability to do daily activities.