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The cephalic flexure, also known as the mesencephalic flexure, is the first flexure or bend, that forms in the region of midbrain. [2] The caudal part of the midbrain and the rostral part of the hindbrain makes up a mibrain-hindbrain boundary region known as the isthmic organizer. [3]
The development of the nervous system in humans, or neural development, or neurodevelopment involves the studies of embryology, developmental biology, and neuroscience.These describe the cellular and molecular mechanisms by which the complex nervous system forms in humans, develops during prenatal development, and continues to develop postnatally.
In a later stage of development the superior part of the neural tube flexes at the level of the future midbrain—the mesencephalon, at the mesencephalic flexure or cephalic flexure. Above the mesencephalon is the prosencephalon (future forebrain) and beneath it is the rhombencephalon (future hindbrain).
The mesencephalic locomotor region (MLR) is a functionally defined area of the midbrain that is associated with the initiation and control of locomotor movements in vertebrate species. [ 1 ] [ 2 ] Neuroanatomical organization
The midbrain or mesencephalon is the uppermost portion of the brainstem connecting the diencephalon and cerebrum with the pons. [2] It consists of the cerebral peduncles, tegmentum, and tectum.
The alar plate (or alar lamina) is a neural structure in the embryonic nervous system, part of the dorsal side of the neural tube, that involves the communication of general somatic and general visceral sensory impulses.
The cerebral aqueduct (aqueduct of the midbrain, aqueduct of Sylvius, Sylvian aqueduct, mesencephalic duct) is a small, narrow tube connecting the third and fourth ventricles of the brain. [ 1 ] [ 2 ] The cerebral aqueduct is a midline structure that passes through the midbrain .
The mesencephalic nucleus is the only structure in the central nervous system to contain the cell bodies of first order sensory neurons. [2] The mesencephalic nucleus can thus be considered functionally as a primary sensory ganglion embedded within the brainstem , [ 1 ] making it neuroanatomically unique.