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Annonacin is a disabling and potentially lethal neurotoxin. [4] [5] [6] Like other acetogenins, it is a mitochondrial complex I (NADH-dehydrogenase) inhibitor. [5]As NADH-dehydrogenase is responsible for the conversion of NADH to NAD+ as well as the establishment of a proton gradient in the mitochondria, annonacin disables the ability of a cell to generate ATP through oxidative phosphorylation ...
Soursop (also called graviola, guyabano, and in Latin America guanábana) is the fruit of Annona muricata, a broadleaf, flowering, evergreen tree. [4] [5] It is native to the tropical regions of the Americas and the Caribbean and is widely propagated. [5] It is in the same genus, Annona, as cherimoya and is in the Annonaceae family.
The U.S. National Cancer Institute notes "Cannabis is not approved by the FDA for the treatment of any cancer-related symptom or side effect of cancer therapy." [61] Cansema (also called black salve) – a type of paste or poultice often promoted as a cancer cure, especially for skin cancer.
The acetogenin compounds, which occur in the fruit, seeds, and leaves of many Annonaceae, including soursop (Annona muricata), are neurotoxins and seem to be the cause of a neurodegenerative disease. The disorder is a so-called tauopathy associated with a pathologic accumulation of tau protein in the brain.
As of 2019, only 32.9% of cancer patients in the United States died within five years of their diagnosis. [7] Despite their effectiveness, many conventional treatments are accompanied by a wide range of side effects, including pain, fatigue, and nausea. [8] [9] Some side effects can even be life-threatening.
There can be many years between promising laboratory work and the availability of an effective anti-cancer drug: Monroe Eliot Wall discovered anti-cancer properties in Camptotheca in 1958, but it was not until 1996 – after further research and rounds of clinical trials – that topotecan, a synthetic derivative of a chemical in the plant, was ...
Grape therapy or grape diet, also known as ampelotherapy, is a diet that involves heavy consumption of grapes, including seeds, and parts of the vine, including leaves, that is a form of alternative medicine.
Oxalis pes-caprae, commonly known as African wood-sorrel, Bermuda buttercup, Bermuda sorrel, buttercup oxalis, Cape sorrel, English weed, goat's-foot, sourgrass, soursob or soursop; Afrikaans: suring; Arabic: hommayda (حميضة), [2] is a species of tristylous yellow-flowering plant in the wood sorrel family Oxalidaceae.