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The first-ever needle-free alternative to the EpiPen and similar epinephrine autoinjectors has been approved by the Food and Drug Administration to treat anaphylaxis.. Neffy, a nasal spray that ...
The nasal-spray Neffy was rejected by the FDA. The epinephrine nasal spray would've been the first needle-free alternative to EpiPens, but the FDA said additional research was needed.
Aug. 26—Those at risk of a severe allergic reaction always have handy an EpiPen just in case. But soon their life might be saved by a spray in the nose rather than a needle to the thigh.
In the updated guidance, NICE recommended the provision of specialist services for "rapidly increasing numbers of steroid users", and that needles should be provided to people under the age of 18—a first for NICE—following reports of 15-year-old steroid injectors seeking to develop their muscles. [19]
Epinephrine vial 1 mg (Adrenalin). Epinephrine is used to treat a number of conditions, including cardiac arrest, anaphylaxis, and superficial bleeding. [25] It has been used historically for bronchospasm and low blood sugar, but newer treatments for these that are selective for β 2 adrenoceptors, such as salbutamol, are preferred.
The first modern epinephrine autoinjector, the EpiPen, was invented in the mid-1970s at Survival Technology in Bethesda, Maryland, US by Sheldon Kaplan [11] [12] and was first approved for marketing by the FDA in 1987. [13] One of the people who helped in making the EpiPen was Richard B. Toren.
Research shows that the vaccine is most effective in the first year and wanes over 10 years. “The best time to get your shingles vaccine is your 50th birthday,” Dr. Kavasery says.
Historically, pen needles were manufactured in lengths up to 12.7mm. Over time, pen needles designed for insulin pens have become shorter, and a 4mm long needle is considered sufficient for most people to administer subcutaneously correctly. [23] In 1989, an injector pen form of human growth hormone was licensed in New Zealand. [28]