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  2. AL amyloidosis - Wikipedia

    en.wikipedia.org/wiki/AL_amyloidosis

    Amyloid light-chain (AL) amyloidosis, ... in systemic AL amyloidosis with 60–70% of people having kidney involvement. ... later with 5 year survival rates also ...

  3. Amyloidosis - Wikipedia

    en.wikipedia.org/wiki/Amyloidosis

    Survival diminishes with increasing stage, but recent advancements in treatments have improved median survival rates for stages I, II, and III, to 91.2, 60, and 7 months respectively. [45] Outcomes in a person with AA amyloidosis depend on the underlying disease, organ(s) affected, and correlate with the concentration of serum amyloid A protein ...

  4. Cardiac amyloidosis - Wikipedia

    en.wikipedia.org/wiki/Cardiac_amyloidosis

    Light chain (AL-CM) Prognosis: For light-chain amyloidosis early detection leads to best possibility of therapies prolonging the period of remission. [3] Well treated light chain cardiac amyloidosis has a 4-year survival rate of around 90%. [5] In patients that undergo stem cell transplant the average survival time increases to 10 years. [5]

  5. Plasma cell dyscrasias - Wikipedia

    en.wikipedia.org/wiki/Plasma_cell_dyscrasias

    Light chain multiple myeloma is diagnosed in patients who have: a) the criteria for diagnosis of multiple myeloma except having a serum free light chain ratio outside the normal range of 0.26 to 1.65 without evidence of an intact immunoglobulin or free heavy chain; or b) an extreme free light chain ratio, i.e. outside the range of 0.02 to 100 ...

  6. Amyloid - Wikipedia

    en.wikipedia.org/wiki/Amyloid

    To date, 37 human proteins have been found to form amyloid in pathology and be associated with well-defined diseases. [2] The International Society of Amyloidosis classifies amyloid fibrils and their associated diseases based upon associated proteins (for example ATTR is the group of diseases and associated fibrils formed by TTR). [3]

  7. The U.S. has the widest health span-lifespan gap - AOL

    www.aol.com/lifestyle/u-biggest-lifespan-health...

    Researchers found that people worldwide live 9.6 years longer than they are healthy — and in the U.S. the gap is more than 12 years.

  8. Monoclonal gammopathy of renal significance - Wikipedia

    en.wikipedia.org/wiki/Monoclonal_gammopathy_of...

    AL amyloidosis is an immunoglobulin light chain associated amyloidosis that involves the deposition of misfolded amyloid light chain (AL) immunoglobulins. These AL light chains are misfolded leading to the disordered deposition of amyloid multimers and fibrils in the glomeruli and blood vessels of the kidney. [ 3 ]

  9. Wild-type transthyretin amyloid - Wikipedia

    en.wikipedia.org/wiki/Wild-Type_Transthyretin...

    Wild-type transthyretin amyloid (WTTA), also known as senile systemic amyloidosis (SSA), [1] is a disease that typically affects the heart and tendons of elderly people. It is caused by the accumulation of a wild-type (that is to say a normal ) protein called transthyretin .

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