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Vesicle: A vesicle or bleb is a small blister, [31] a circumscribed, epidermal elevation generally considered less than either 5 [10] or 10 mm in diameter at the widest point. [30] Bulla: A bulla is a large blister, [31] a rounded or irregularly shaped blister equal to or greater than either 5 [10] or 10 mm, [30] depending on one's definition ...
[19] [20] Clinically, the diagnosis of any particular skin condition is made by gathering pertinent information regarding the presenting skin lesion(s), including the location (such as arms, head, legs), symptoms (pruritus, pain), duration (acute or chronic), arrangement (solitary, generalized, annular, linear), morphology (macules, papules ...
A papule can be flesh colored, yellow, white, brown, black, blue or purplish, or varying shades of red. [4] [6] The intensity of redness might indicate how long the papule has been present. [6] There may be just one or many, and they may occur irregularly in different parts of the body or appear in clusters. [2] It may progress to a pustule or ...
Target lesions are the typical lesions of erythema multiforme, in which a vesicle is surrounded by an often hemorrhagic maculopapule. Erythema multiforme is often self-limited, of acute onset, resolves in three to six weeks, and has a cyclical pattern. Its lesions are multiform (polymorphous) and include macules, papules, vesicles, and bullae.
Histopathological image of dyshidrotic dermatitis, showing focal spongiotic change in the epidermis. Spongiosis is mainly intercellular [1] edema (abnormal accumulation of fluid) in the epidermis, [2] and is characteristic of eczematous dermatitis, manifested clinically by intraepidermal vesicles (fluid-containing spaces), "juicy" papules, and/or lichenification. [3]
The main symptoms include several kinds of skin rash along with muscle weakness in both upper arms or thighs. [8] Although dermatomyositis is closely related to polymyositis and is sometimes assumed to be a complication of that disease, most patients with dermatomyositis develop skin symptoms before any muscle involvement.
Initially red to pink, flat spots (formally, "macules") and raised bumps (formally, "papules") may be seen on the skin. [5] [6] Once fully developed, the classic appearance is "non-blanching, palpable purpura". [6] [5] [7] This appears as deep red to purple spots that feel raised to the touch. Purpura refers to the red-purple discolored spots ...
In this case, the central portion is a complex papule, and the periphery is macular, irregular, indistinct and slightly pink. Characteristic rete ridge bridging, shouldering, and lamellar fibrosis. H&E stain. Blue nevus: It is blue in color as its melanocytes are very deep in the skin. Characteristic pigmented melanocytes between bundles of ...