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β-Hydroxy β-methylbutyric acid [note 1] (HMB), otherwise known as its conjugate base, β-hydroxy β-methylbutyrate, is a naturally produced substance in humans that is used as a dietary supplement and as an ingredient in certain medical foods that are intended to promote wound healing and provide nutritional support for people with muscle wasting due to cancer or HIV/AIDS.
L-arginine is recognized as safe (GRAS-status) at intakes of up to 20 grams per day. [51] L-arginine is found in many foods, such as fish, poultry, and dairy products, and is used as a dietary supplement. [52] It may interact with various prescription drugs and herbal supplements. [52]
Chemical formula: C 6 H 14 N 4 O 2 Molar mass: 174.2 g·mol −1 Systematic name: 2-amino-5-(diaminomethylidene amino)pentanoic acid Abbreviations: R, Arg Synonyms: 2-amino-5-guanidinopentanoic acid
Over the period of 1999 to 2012, use of multivitamins decreased, and there was wide variability in the use of individual supplements among subgroups by age, sex, race/ethnicity, and educational status. [144] Particular attention has been given to use of folate supplements by young women to reduce the risk of fetal neural tube defects. [145] [146]
[28] [29] Active targeting strategies aim to increase drug transport into cells to improve efficacy and counter multidrug resistance. [ 28 ] In addition to doxorubicin, RGD-conjugated nanomaterials have been used to deliver the chemotherapeutics cisplatin , docetaxel , paclitaxel , 5-fluorouracil , and Gemcitabine to cancer cells.
Over time, a deficiency of B12 can cause problems with balance, confusion, depression, poor memory and possibly dementia, and it can even cause permanent damage to the nervous system, Somers says.
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