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Buprenorphine/naloxone, sold under the brand name Suboxone among others, is a fixed-dose combination medication that includes buprenorphine and naloxone. [3] It is used to treat opioid use disorder, and reduces the mortality of opioid use disorder by 50% (by reducing the risk of overdose on full-agonist opioids such as heroin or fentanyl).
Buprenorphine, sold under the brand name Subutex among others, is an opioid used to treat opioid use disorder, acute pain, and chronic pain. [18] It can be used under the tongue (sublingual), in the cheek (buccal), by injection (intravenous and subcutaneous), as a skin patch (transdermal), or as an implant.
An opioid overdose is toxicity due to excessive consumption of opioids, such as morphine, codeine, heroin, fentanyl, tramadol, and methadone. [3] [5] This preventable pathology can be fatal if it leads to respiratory depression, a lethal condition that can cause hypoxia from slow and shallow breathing. [3]
More than 200 people in Mecklenburg County died from drug overdoses last year, according to data from the N.C. Department of Health and Human Services.
Opioid prescriptions have dropped in every state over the last decade, but the effort to prevent overdose deaths is an abject failure Why Overdose Deaths Skyrocketed After Opioid Prescriptions Dropped
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To prevent this, small doses every few minutes can be given until the desired effect is reached. [13] In those with previous heart disease or taking medications that negatively affect the heart, further heart problems have occurred. [13] It appears to be safe in pregnancy, after having been given to a limited number of women. [16]
On a community level, established safe injection sites that provide a hygienic space supervised by licensed healthcare professionals allow for safe monitoring of participants and provide health education and care to prevent overdose. Another way to help prevent overdose, especially regarding opioids, is the increased access and knowledge of ...