Search results
Results from the WOW.Com Content Network
Batrachotoxin was discovered by Fritz Märki and Bernhard Witkop, at the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Bethesda, Maryland, U.S.A. Märki and Witkop separated the potent toxic alkaloids fraction from Phyllobates bicolor and determined its chemical properties in 1963. [4]
The toxin was also referenced in "synthetic form" in season 1, episode 2, of the series "FBI". The toxin is used as a weapon in both the second season of Archer , in Covert Affairs and in the Inside No. 9 episode " The Riddle of the Sphinx ".
Some estimates of lethality with BZ have been grossly erroneous, and ultimately the safety margin for BZ is inconclusive due to lack of human data at higher dosage ranges, though some researchers have estimated it to be 0.5 to 3.0 mg/kg and an LD 01 is 0.2 to 1.4 mg/kg (Rosenblatt, Dacre, Shiotsuka, & Rowlett, 1977).
Toxic shock syndrome toxin-1 (TSST-1) is a superantigen with a size of 22 kDa [1] produced by 5 to 25% of Staphylococcus aureus isolates. It causes toxic shock syndrome (TSS) by stimulating the release of large amounts of interleukin-1, interleukin-2 and tumor necrosis factor. In general, the toxin is not produced by bacteria growing in the ...
An immunotoxin is an artificial protein consisting of a targeting portion linked to a toxin. When the protein binds to that cell, it is taken in through endocytosis, and the toxin kills the cell. [1] They are used for the treatment of some kinds of cancer and a few viral infections.
Loss of an affected limb is possible even with prompt treatment. Haemotoxins are frequently employed by venomous animals, including snakes ( vipers and pit vipers ) and spiders ( brown recluse ). Animal venoms contain enzymes and other proteins that are haemotoxic or neurotoxic or occasionally both (as in the Mojave rattlesnake , the Japanese ...
Alimentary toxic aleukia is a mycotoxin-induced condition characterized by nausea, vomiting, diarrhea, leukopenia (aleukia), hemorrhaging, skin inflammation, and sometimes death. [1] Alimentary toxic aleukia almost always refers to the human condition associated with presence of T-2 Toxin. [1]
A dose of 10 5 pfu of poneratoxin was sufficient to kill the S. frugiperda larvae, and a dose of 10 ng could paralyze them. [1] Based on these experiments, scientists believe poneratoxin can make a good candidate as a bio- insecticide because of its neurotoxicity to other insects, making it capable of immobilizing or even killing insects ...