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Moxidectin is an anthelmintic drug used in animals to prevent or control parasitic worms , such as heartworm and intestinal worms, in dogs, cats, horses, cattle, sheep and wombats. [4] Moxidectin kills some of the most common internal and external parasites by selectively binding to a parasite's glutamate-gated chloride ion channels .
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Avermectins (including ivermectin and moxidectin) - effective against most common intestinal worms, except tapeworms, for which praziquantel is commonly used in conjunction for mass dewormings; Drugs not members of these three main categories include: Diethylcarbamazine – effective against Wuchereria bancrofti, Brugia malayi, Brugia timori ...
flunixin meglumine – nonsteroidal anti-inflammatory drug used as an analgesic and antipyretic in horses; fluralaner - antiparasitic; frunevetmab - nerve growth factor inhibitor monoclonal antibody used for osteoarthritis in cats; furosemide – diuretic used to prevent exercise-induced pulmonary hemorrhage in horses
Heartworm prevention for cats is available as ivermectin (Heartgard for Cats), milbemycin (Interceptor), or the topical selamectin (Revolution for Cats) and Advantage Multi (imidacloprid + moxidectin) topical solution. Ivermectin, milbemycin, and selamectin are approved for use in cats in the US. [citation needed]
The US Food and Drug Administration (FDA) approved it for flea treatment in dogs in May 2014, [17] and approved the combination fluralaner/moxidectin (Bravecto Plus) as a topical treatment for cats in November 2019.
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